Brain infections may spark Alzheimer’s, new study suggests

While still speculative, new hypothesis offers some sensible explanations to the disease.

Strands of beta amyloid fibrils form around yeast in culture media. (credit: Credit: D.K.V. Kumar et al. / Science Translational Medicine (2016)])

The protein globs that jam brain circuits in people with Alzheimer’s disease may not result from a sloppy surplus, but rather a bacterial battle, a new study suggests.

Previously, researchers assumed that the protein—beta amyloid—was just a junk molecule that piled up. And efforts to cure Alzheimer’s focused on clearing out clogs and banishing beta amyloid from the brain. But a new study conducted using mice and worms suggests that the protein clumps are actually microbial booby traps, sturdy proteinaceous snares intended to confine invading microbes and protect the brain.

The findings, published in the journal Science Translational Medicine, suggest that Alzheimer’s may result from the brain’s effort to fight off infections. While that hypothesis is controversial and highly speculative at this point, it could dramatically alter the way researchers and doctors work to treat and prevent the degenerative disease.

Read 6 remaining paragraphs | Comments

Internetwirtschaft: Das ist so was von 2006

Die richtigen Fragen, nur zehn Jahre zu spät: Das “Grünbuch Digitale Plattformen” des Wirtschaftsministeriums zeigt den Abstand der deutschen Netzpolitik zur Realität. (Netzpolitik, Internet)

Die richtigen Fragen, nur zehn Jahre zu spät: Das "Grünbuch Digitale Plattformen" des Wirtschaftsministeriums zeigt den Abstand der deutschen Netzpolitik zur Realität. (Netzpolitik, Internet)

NVM Express und U.2: Supermicro gibt SATA- und SAS-SSDs bald auf

Wenn es um Rechenzentrumshardware geht, sind traditionelle SSDs für Supermicro viel zu langsam. Das Unternehmen wechselt von SSD All Flash auf All NVMe Flash. Helfen soll die breite Verwendung von U.2 alias SFF-8639. (NVMe, Speichermedien)

Wenn es um Rechenzentrumshardware geht, sind traditionelle SSDs für Supermicro viel zu langsam. Das Unternehmen wechselt von SSD All Flash auf All NVMe Flash. Helfen soll die breite Verwendung von U.2 alias SFF-8639. (NVMe, Speichermedien)

100 MBit/s: Telekom bringt 10.000 Haushalten in Großstadt Vectoring

Einem Bezirk einer deutschen Großstadt Vectoring zu bringen bedeutet, 13 Kilometer Glasfaserleitungen neu zu verlegen und 30 Schaltverteiler auf- oder auszubauen. Die Telekom baut zurzeit in vielen Städten aus. (Vectoring, DSL)

Einem Bezirk einer deutschen Großstadt Vectoring zu bringen bedeutet, 13 Kilometer Glasfaserleitungen neu zu verlegen und 30 Schaltverteiler auf- oder auszubauen. Die Telekom baut zurzeit in vielen Städten aus. (Vectoring, DSL)

If climate scientists are in it for the money, they’re doing it wrong

Ars takes a look at the accusations that climate scientists push the consensus.

It's Memorial Day, all Ars staff is off, and we're grateful for it (running a site remains tough work). But on a normal Monday, inevitably we'd continue to monitor news from the world of climate change. Our John Timmer examined the claims that scientists are in it solely for the money in February 2011, and we're resurfacing his piece for your holiday reading pleasure.

One of the more unfortunate memes that makes an appearance whenever climate science is discussed is the accusation that, by hyping their results, climate scientists are ensuring themselves steady paychecks, and may even be enriching themselves. A Google search for "global warming gravy train" pulls out over 50,000 results (six of them from our forums).

It's tempting to respond with indignation; after all, researchers generally are doing something they love without a focus on compensation. But, more significantly, the accusation simply makes no sense on any level.

Read 18 remaining paragraphs | Comments

A gratuitous gallery of warbirds for Memorial Day

Celebrating Memorial Day with a trip to the National Museum of the US Air Force.


Americans have honored those lost in war in some shape or another since just after the Civil War. Memorial Day as we know it—a federal holiday on the last Monday in May—is more recent, dating back to 1968. But the sentiment is the same—remembering those who paid the ultimate price in defense of their country. Since a recent trip happened to take us by the National Museum of the United States Air Force in Dayton, Ohio, we've decided to celebrate it here at Ars by bringing you this gallery of some fine-looking warbirds.

The museum can be found at Wright-Patterson Air Force Base. It's truly vast—even giants of the air like the B-36 and B-52 can seem small underneath the roof of one of its hangars. It also has some rather significant planes in its collection, notably Bockscar, one of the two B-29s that dropped atom bombs on Japan in World War II (the Enola Gay lives at the Smithsonian's Udvar-Hazy collection in Dulles, VA).

The collections under those massive hangers are organized chronologically, from the beginning of flight through World War II, Korea, Vietnam, the Cold War, through to today. Sadly, we weren't able to check out one of the museum's most fascinating aircraft, the remaining North American XB-70 Valkyrie; the new hanger for research and experimental aircraft (and old Air Force Ones) doesn't open until next week.

Read on Ars Technica | Comments

YouTube Threatens Legal Action Against Video Downloader

YouTube continues to crack down on sites and services that allow people to download videos from the site. Most recently, YouTube urged the operator of TubeNinja to cease his activities, or face potential legal action instead. For now, however, the video download service has no plans to change its course.

Source: TF, for the latest info on copyright, file-sharing, torrent sites and ANONYMOUS VPN services.

sadyoutubeWith over a billion users YouTube is the largest video portal on the Internet.

Every day users watch hundreds of millions of hours of video on the site, and for many it’s a prime source to enjoy music as well.

While YouTube is a blessing to thousands of content creators, there are also concerns among rightsholders. Music labels in particular are not happy with the fact that music videos can be easily downloaded from the site with help from external services.

To address the problem YouTube is contacting these third party sites, urging them to shut down this functionality. Most recently, YouTube’s legal team contacted the popular download service TubeNinja.

“It appears from your website and other marketing materials that TubeNinja is designed to allow users to download content from YouTube,” the email from YouTube’s legal team reads.

According to YouTube the video downloader violates the terms of service (ToS) of both the site and the API. Among other things, YouTube’s ToS prohibits the downloading of any video that doesn’t have a download link listed on the site.

Later, Google’s video service adds that if the site owner continues to operate the service this “may result in legal consequences.”

Email from YouTube’s legal team

youlett2

Despite the threatening language, TubeNinja owner Nathan doesn’t plan to take the functionality offline. He informed YouTube that his service doesn’t use YouTube’s API and says that it’s the responsibility of his users to ensure that they don’t violate the ToS of YouTube and TubeNinja.

“Our own ToS clearly states that the user is responsible for the legitimacy of the content they use our service for,” Nathan tells us.

TubeNinja doesn’t believe that YouTube has a very strong case and Nathan has asked the company for clarification. He also mentions that Google’s very own Chrome service lists many plugins that offer the exact same functionality.

“They don’t even seem to enforce removal of Chrome plugins that enable users to do the exact same thing,” Nathan says.

“Also the fact that services like Savefrom, Keepvid, clipconverter etc have been around since 2008, we find it hard to believe that there is any legal case at all. Kind of like suing a maker of VHS-recorders for users taping the television broadcast,” he adds.

This isn’t the first time that YouTube has taken action against download services. The site has gone after similar sites in the past

In 2012 Google went after Youtube-mp3.org with a message similar to the one TubeNinja received, but despite these efforts the site remains one of the most used conversion tools with millions of visitors per day.

Source: TF, for the latest info on copyright, file-sharing, torrent sites and ANONYMOUS VPN services.

Zum Weltnichtrauchertag: BSI warnt vor Malware in E-Zigaretten

Wer E-Zigaretten raucht, erspart seiner Lunge Teer, setzt aber die Gesundheit seines Rechners aufs Spiel – zumindest, wenn die E-Zigarette per USB aufgeladen wird. (BSI, Virus)

Wer E-Zigaretten raucht, erspart seiner Lunge Teer, setzt aber die Gesundheit seines Rechners aufs Spiel - zumindest, wenn die E-Zigarette per USB aufgeladen wird. (BSI, Virus)

The spammer who logged into my PC and installed Microsoft Office

Spam text made a tempting offer—so I let the spammer take control of my PC.

(credit: Aurich Lawson / Thinkstock)

It's Memorial Day, all Ars staff is off, and we're grateful for it (running a site remains tough work). But on a normal Monday, inevitably we'd continue to monitor the security world. Our Jon Brodkin willingly embraced a firsthand experience with low-grade scammers in April 2013, and we're resurfacing his piece for your holiday reading pleasure.

It all began with an annoying text message sent to an Ars reader. Accompanied by a Microsoft Office logo, the message came from a Yahoo e-mail address and read, "Hi, Do u want Microsoft Office 2010. I Can Remotely Install in a Computer."

An offer I couldn't refuse.

The recipient promptly answered "No!" and then got in touch with us. Saying the spam text reminded him of the "'your computer has a virus' scam," the reader noted that "this seems to be something that promises the same capabilities, control of your computer and a request for your credit card info. Has anyone else seen this proposal?"

Read 22 remaining paragraphs | Comments

Deals of the Day (5-30-2016)

There a lot of Chromebooks that you can buy for under $200, but at that price you usually get a machine with just 2GB of RAM and a 1366 x 768 pixel display.
This holiday weekend Best Buy is offering something a little better: a Toshiba Chromebook 2 wit…

Deals of the Day (5-30-2016)

There a lot of Chromebooks that you can buy for under $200, but at that price you usually get a machine with just 2GB of RAM and a 1366 x 768 pixel display.

This holiday weekend Best Buy is offering something a little better: a Toshiba Chromebook 2 with a 13.3 inch, 1920 x 1080 pixel display and 4GB of RAM for $199. Sure, the notebook has just 16GB of storage, but that should be plenty of space for Chrome OS.

Continue reading Deals of the Day (5-30-2016) at Liliputing.