How different mushrooms learned the same psychedelic trick

Scientists may have additional tools to produce psilocybin to use for medical purposes.

Magic mushrooms have been used in traditional ceremonies and for recreational purposes for thousands of years. However, a new study has found that mushrooms evolved the ability to make the same psychoactive substance twice. The discovery has important implications for both our understanding of these mushrooms’ role in nature and their medical potential.

Magic mushrooms produce psilocybin, which your body converts into its active form, psilocin, when you ingest it. Psilocybin rose in popularity in the 1960s and was eventually classed as a Schedule 1 drug in the US in 1970, and as a Class A drug in 1971 in the UK, the designations given to drugs that have high potential for abuse and no accepted medical use. This put a stop to research on the medical use of psilocybin for decades.

But recent clinical trials have shown that psilocybin can reduce depression severity, suicidal thoughts, and chronic anxiety. Given its potential for medical treatments, there is renewed interest in understanding how psilocybin is made in nature and how we can produce it sustainably.

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(g+) Der vernetzte Arbeitsplatz: Wie MCP die Arbeit mit KI-Agenten verändert

MCP ist ein bemerkenswertes Protokoll, das die Schnittstelle zwischen verschiedenen KI-Modellen standardisiert: Wir erklären, wie man es sinnvoll nutzen kann. Ein Praxistest von Markus Kammermeier (KI, API)

MCP ist ein bemerkenswertes Protokoll, das die Schnittstelle zwischen verschiedenen KI-Modellen standardisiert: Wir erklären, wie man es sinnvoll nutzen kann. Ein Praxistest von Markus Kammermeier (KI, API)

Alien Earth: Xenomorph-Monster zum Schoßhund degradiert

Nach begeisterndem Start endet Staffel 1 von Alien: Earth ärgerlich schlecht und veranschaulicht damit ein Grundproblem für Serienkritiker. Eine Rezension von Daniel Pook (Filme & Serien, Disney)

Nach begeisterndem Start endet Staffel 1 von Alien: Earth ärgerlich schlecht und veranschaulicht damit ein Grundproblem für Serienkritiker. Eine Rezension von Daniel Pook (Filme & Serien, Disney)

Nearly 80% of Americans want Congress to extend ACA tax credits, poll finds

Without the extension, premiums for plans on the ACA Marketplace will more than double.

According to new polling data, nearly 80 percent of Americans support extending Affordable Care Act (ACA) enhanced premium tax credits, which are set to expire at the end of this year—and are at the center of a funding dispute that led to a shutdown of the federal government this week.

The poll, conducted by KFF and released Friday, found that 78 percent of Americans want the tax credits extended, including 92 percent of Democrats, 59 percent of Republicans—and even a majority (57 percent) of Republicans who identify as Donald Trump-aligned MAGA (Make America Great Again) supporters.

A separate analysis published by KFF earlier this week found that if the credits are not extended, monthly premiums for ACA Marketplace plans would more than double on average. Specifically, the current average premium of $888 would jump to $1,904 in 2026, a 114 percent increase.

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Removing these 50 objects from orbit would cut danger from space junk in half

“In their rush to move quickly, they are adding to the long-term collision hazard.”

A new listing of the 50 most concerning pieces of space debris in low-Earth orbit is dominated by relics more than a quarter-century old, primarily dead rockets left to hurtle through space at the end of their missions.

"The things left before 2000 are still the majority of the problem," said Darren McKnight, lead author of a paper presented Friday at the International Astronautical Congress in Sydney. "Seventy-six percent of the objects in the top 50 were deposited last century, and 88 percent of the objects are rocket bodies. That's important to note, especially with some disturbing trends right now."

The 50 objects identified by McKnight and his coauthors are the ones most likely to drive the creation of more space junk in low-Earth orbit (LEO) through collisions with other debris fragments. The objects are whizzing around the Earth at nearly 5 miles per second, flying in a heavily trafficked part of LEO between 700 and 1,000 kilometers (435 to 621 miles) above the Earth.

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