Month: October 2024

A stunning image of differentiated mouse brain tumor cells has won the 2024 Nikon Small World photomicrography contest, yielding valuable insight into how degenerate diseases like Alzheimer's and ALS can arise from disruption in the cytoskeleton of brain cells. The image was taken by Bruno Cisterna, with assistance from Eric Vitriol, both with Augusta University in Georgia.

"One of the main problems with neurodegenerative diseases is that we don't fully understand what causes them,” Cisterna said in a statement. “To develop effective treatments, we need to figure out the basics first. Our research is crucial for uncovering this knowledge and ultimately finding a cure. Differentiated cells could be used to study how mutations or toxic proteins that cause Alzheimer's or ALS alter neuronal morphology, as well as to screen potential drugs or gene therapies aimed at protecting neurons or restoring their function.”

It's the 50th anniversary of Nikon's annual contest, which was founded back in 1974 "to showcase the beauty and complexity of things seen through the light microscope." Photomicrography involves attaching a camera to a microscope (either an optical microscope or an electron microscope) so that the user can take photographs of objects at very high resolutions. British physiologist Richard Hill Norris was one of the first to use it for his studies of blood cells in 1850, and the method has increasingly been highlighted as art since the 1970s. There have been many groundbreaking technological advances in the ensuing decades, particularly with the advent of digital imaging methods.

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AI software company Anthropic has announced a new tool that can take control of the user's mouse cursor and perform basic tasks on their computer.

Announced alongside other improvements to Anthropic's Claude and Haiku models, the tool is straightforwardly called "Computer Use." It's available exclusively with the company's mid-range 3.5 Sonnet model right now, via the API. Users can give multi-step instructions (Anthropic claims it can go for tens or even hundreds of steps) to accomplish tasks on the user's computer by "looking at a screen, moving a cursor, clicking buttons, and typing text."

Here's how Anthropic says it works:

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Police use of automated license-plate reader cameras is being challenged in a lawsuit alleging that the cameras enable warrantless surveillance in violation of the Fourth Amendment. The city of Norfolk, Virginia, was sued yesterday by plaintiffs represented by the Institute for Justice, a nonprofit public-interest law firm.

Norfolk, a city with about 238,000 residents, "has installed a network of cameras that make it functionally impossible for people to drive anywhere without having their movements tracked, photographed, and stored in an AI-assisted database that enables the warrantless surveillance of their every move. This civil rights lawsuit seeks to end this dragnet surveillance program," said the complaint filed in US District Court for the Eastern District of Virginia.

Like many other cities, Norfolk uses cameras made by the company Flock Safety. A 404 Media article said Institute for Justice lawyer Robert Frommer "told 404 Media that the lawsuit could have easily been filed in any of the more than 5,000 communities where Flock is active, but that Norfolk made sense because the Fourth Circuit of Appeals—which Norfolk is part of—recently held that persistent, warrantless drone surveillance in Baltimore is unconstitutional under the Fourth Amendment in a case called Beautiful Struggle v Baltimore Police Department."

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Fortinet, a maker of network security software, has kept a critical vulnerability under wraps for more than a week amid reports that attackers are using it to execute malicious code on servers used by sensitive customer organizations.

Fortinet representatives didn’t respond to emailed questions and have yet to release any sort of public advisory detailing the vulnerability or the specific software that’s affected. The lack of transparency is consistent with previous zero-days that have been exploited against Fortinet customers. With no authoritative source for information, customers, reporters, and others have few other avenues for information other than social media posts where the attacks are being discussed.

RCE stands for remote code execution

According to one Reddit post, the vulnerability affects FortiManager, a software tool for managing all traffic and devices on an organization’s network. Specific versions vulnerable, the post said, include FortiManager versions:

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AMD’s been making laptop processors for years that have integrated graphics powerful enough to let you play many recent games without a discrete GPU. And in 2023 the company released its first Ryzen Z series processors designed specifically for handheld gaming PCs like the Asus ROG Ally and Lenovo Legion Go. Recently AMD officials confirmed plans to […]

The post AMD’s Ryzen Z2 chips could bring Strix Point graphics to handhelds in 2025 (Updated) appeared first on Liliputing.

Like Frodo himself, I wasn't sure we were going to make it all the way to the end of our quest. But this week, my family crossed an important life threshold: every member has now heard J.R.R. Tolkien's Lord of the Rings (LotR) read aloud—and sung aloud—in its entirety.

Five years ago, I read the series to my eldest daughter; this time, I read it for my wife and two younger children. It took a full year each time, reading 20–45 minutes before bed whenever we could manage it, to go "there and back again" with our heroes. The first half of The Two Towers, with its slow-talking Ents and a scattered Fellowship, nearly derailed us on both reads, but we rallied, pressing ahead even when iPad games and TV shows appeared more enticing. Reader, it was worth the push.

Gollum's ultimate actions on the edge of the Crack of Doom, the final moments of Sauron and Saruman as impotent mists blown off into the east, Frodo's woundedness and final ride to the Grey Havens—all of it remains powerful and left a suitable impression upon the new listeners.

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Qualcomm has a new chip for flagship phones, and the best part is that it uses an improved version of the Oryon CPU architecture that the Snapdragon X Elite chips brought to Windows PCs earlier this year.

The Snapdragon 8 Elite is the follow-up to last year's Snapdragon 8 Gen 3—yet another change to the naming convention that Qualcomm uses for its high-end phone chips, though, as usual, the number 8 is still involved. The 8 Elite uses a "brand-new, 2nd-generation Qualcomm Oryon CPU" with clock speeds up to 4.32 GHz, which Qualcomm says will improve performance by about 45 percent compared to the Snapdragon 8 Gen 3.

Rather than a mix of large, medium, and small CPU cores as it has used in the past, the 8 Elite has two "Prime" cores for hitting that high peak clock speed, while the other six are all "Performance" cores that peak at a lower 3.53 GHz. But it doesn't look like Qualcomm is using a mix of different CPU architectures anymore, choosing to distinguish the higher-performing core from the lower-performing ones by clock speed alone.

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Elon Musk may have personally used AI to rip off a Blade Runner 2049 image for a Tesla cybercab event after producers rejected any association between their iconic sci-fi movie and Musk or any of his companies.

In a lawsuit filed Tuesday, lawyers for Alcon Entertainment—exclusive rightsholder of the 2017 Blade Runner 2049 movie—accused Warner Bros. Discovery (WBD) of conspiring with Musk and Tesla to steal the image and infringe Alcon's copyright to benefit financially off the brand association.

According to the complaint, WBD did not approach Alcon for permission until six hours before the Tesla event when Alcon "refused all permissions and adamantly objected" to linking their movie with Musk's cybercab.

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It's been just over two years now since soon-to-depart CTO John Carmack told a Meta Connect audience about his vision for a super low-end VR headset that came in at $250 and 250 grams. "We're not building that headset today, but I keep trying," Carmack said at the time with some exasperation.

On the pricing half of the equation, the recently released Quest 3S headset is nearly on target for Carmack's hopes and dreams. Meta's new $299 headset is a significant drop from the $499 Quest 3 and the cheapest price point for a Meta VR headset since the company raised the price of the aging Quest 2 to $400 back in the summer of 2022. When you account for a few years of inflation in there, the Quest 3S is close to the $250 headset Carmack envisioned.

A new button on the underside of the Quest 3S lets you transition to pass-through mode at any time.

Credit: Kyle Orland

Unfortunately, Meta must still seriously tackle the "250 grams" part of Carmack's vision. The 514g Quest 3S feels at least as unwieldy on your face as the 515g Quest 3, and both are still quite far from the "super light comforts" Carmack envisioned. Add in all the compromises Meta made so the Quest 3S could hit that lower price point, and you have a cheap, half-measure headset that we can only really recommend to the most price-conscious of VR consumers.

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