Month: April 2024

Enlarge / Takeda Pharmaceutical Co. Adderall XR brand medication arranged at a pharmacy in Provo, Utah, in November 2023. (credit: Getty | George Frey)

Drug shortages in the US have reached an all-time high, with 323 active and ongoing shortages already tallied this year, according to data collected by the American Society of Health-System Pharmacists (ASHP).

The current drug shortage total surpasses the previous record of 320, set in 2014, and is the highest recorded since ASHP began tracking shortages in 2001.

"All drug classes are vulnerable to shortages," ASHP CEO Paul Abramowitz said in a statement Thursday. "Some of the most worrying shortages involve generic sterile injectable medications, including cancer chemotherapy drugs and emergency medications stored in hospital crash carts and procedural areas. Ongoing national shortages of therapies for attention-deficit/hyperactivity disorder [ADHD] also remain a serious challenge for clinicians and patients."

Enlarge / Takeda Pharmaceutical Co. Adderall XR brand medication arranged at a pharmacy in Provo, Utah, in November 2023. (credit: Getty | George Frey)

Drug shortages in the US have reached an all-time high, with 323 active and ongoing shortages already tallied this year, according to data collected by the American Society of Health-System Pharmacists (ASHP).

The current drug shortage total surpasses the previous record of 320, set in 2014, and is the highest recorded since ASHP began tracking shortages in 2001.

"All drug classes are vulnerable to shortages," ASHP CEO Paul Abramowitz said in a statement Thursday. "Some of the most worrying shortages involve generic sterile injectable medications, including cancer chemotherapy drugs and emergency medications stored in hospital crash carts and procedural areas. Ongoing national shortages of therapies for attention-deficit/hyperactivity disorder [ADHD] also remain a serious challenge for clinicians and patients."

Enlarge / Generic, non-Western Digital SD cards. (credit: Getty)

Western Digital plans to release the first 4TB SD card next year. On Thursday, the storage firm announced plans to demo the product in person next week.

Western Digital will launch the SD card, which follows the SD Association's Secure Digital Ultra Capacity (SDUC) standard, under its SanDisk brand and market it toward "complex media and entertainment workflows," such as high-resolution video with high framerates, using cameras and laptops, the announcement said.

The spacious card will use the Ultra High Speed-1 (UHS-1) bus interface, supporting max theoretical transfer rates of up to 104MB per second. It will support minimum write speeds of 10 MB/s, AnandTech reported. Minimum sequential write speeds are expected to reach 30 MB/s, the publication said.

Enlarge (credit: Getty Images)

Highly capable hackers are rooting multiple corporate networks by exploiting a maximum-severity zero-day vulnerability in a firewall product from Palo Alto Networks, researchers said Friday.

The vulnerability, which has been under active exploitation for at least two weeks now, allows the hackers with no authentication to execute malicious code with root privileges, the highest possible level of system access, researchers said. The extent of the compromise, along with the ease of exploitation, has earned the CVE-2024-3400 vulnerability the maximum severity rating of 10.0. The ongoing attacks are the latest in a rash of attacks aimed at firewalls, VPNs, and file-transfer appliances, which are popular targets because of their wealth of vulnerabilities and direct pipeline into the most sensitive parts of a network.

“Highly capable” UTA0218 likely to be joined by others

The zero-day is present in PAN-OS 10.2, PAN-OS 11.0, and/or PAN-OS 11.1 firewalls when they are configured to use both the GlobalProtect gateway and device telemetry. Palo Alto Networks has yet to patch the vulnerability but is urging affected customers to follow the workaround and mitigation guidance provided here. The advice includes enabling Threat ID 95187 for those with subscriptions to the company’s Threat Prevention service and ensuring vulnerability protection has been applied to their GlobalProtect interface. When that’s not possible, customers should temporarily disable telemetry until a patch is available.

Enlarge / An image of a boy amazed by flying letters. (credit: Getty Images)

Some weeks in AI news are eerily quiet, but during others, getting a grip on the week's events feels like trying to hold back the tide. This week has seen three notable large language model (LLM) releases: Google Gemini Pro 1.5 hit general availability with a free tier, OpenAI shipped a new version of GPT-4 Turbo, and Mistral released a new openly licensed LLM, Mixtral 8x22B. All three of those launches happened within 24 hours starting on Tuesday.

With the help of software engineer and independent AI researcher Simon Willison (who also wrote about this week's hectic LLM launches on his own blog), we'll briefly cover each of the three major events in roughly chronological order, then dig into some additional AI happenings this week.

Gemini Pro 1.5 general release

(credit: Google)

On Tuesday morning Pacific time, Google announced that its Gemini 1.5 Pro model (which we first covered in February) is now available in 180+ countries, excluding Europe, via the Gemini API in a public preview. This is Google's most powerful public LLM so far, and it's available in a free tier that permits up to 50 requests a day.

Enlarge (credit: LinkedIn)

An accomplished and prominent transplant surgeon in Texas allegedly falsified patient data in a government transplant waiting list, which may have prevented his own patients from receiving lifesaving liver transplants, according to media reports and hospital statements.

Memorial Hermann-Texas Medical Center halted its liver transplant program on April 3 after finding "irregularities" with donor acceptance criteria, the Houston Chronicle reported based on a statement from the hospital. At the time there were 38 patients on the hospital's wait list for a liver. Earlier this week, the hospital also halted its kidney transplant program, telling the Chronicle that it was pausing operations to "evaluate a new physician leadership structure."

Memorial Hermann has not named the surgeon behind the "inappropriate changes," but The New York Times identified him as Dr. Steve Bynon, a surgeon who has received numerous accolades and, at one point, appears to have been featured on a billboard. Bynon oversaw both the liver and kidney transplant programs at Memorial Hermann.