Pig heart transplanted to human for the first time

Transplant is “compassionate use” rather than part of a clinical trial.

Image of surgeons surrounding a patient.

Enlarge / The transplant team with the replacement heart. (credit: The transplant team with the replacement heart.)

On Monday, the University of Maryland School of Medicine announced that its staff had done the first transplant of a pig's heart into a human. The patient who received it had end-stage heart disease and was too sick to qualify for the standard transplant list. Three days after the procedure, the patient was still alive.

The idea of using non-human organs as replacements for damaged human ones—called xenotransplantation—has a long history, inspired by the fact that there are more people on organ waiting lists than there are donors. And, in recent years, our ability to do targeted gene editing has motivated people to start genetically modifying pigs in order to make them better donors. But the recent surgery wasn't part of a clinical trial, so it shouldn't be viewed as an indication that this approach is ready for widespread safety and efficacy testing.

Instead, the surgery was authorized by the FDA under its "compassionate use" access program. This allows those faced with life-threatening illnesses to receive investigational treatments that haven't gone through rigorous clinical testing yet.

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Apple may be done with Intel Macs, but Hackintoshes can still use the newest CPUs

OpenCore project continues bridging the gaps between PCs and real Intel Macs.

Hackintoshes are PCs that run macOS, which means you can do whatever you want with the design.

Enlarge / Hackintoshes are PCs that run macOS, which means you can do whatever you want with the design. (credit: Dan Counsell)

Apple hasn't stopped selling Intel Macs just yet, but it's safe to say that we'll never see a Mac with one of Intel's 12th-generation Core processors in it. But that minor detail isn't stopping the Hackintosh community from supporting new Intel and AMD processors and platforms. The developers behind OpenCore, the most powerful and actively maintained bootloader for loading macOS on standard PC hardware, improved its Alder Lake support in this month's release, version 0.7.7. In a blog post over the weekend, the developers also detailed their efforts to update OpenCore and its associated software to work with Intel's Z690 chipset.

The key to building a functional Hackintosh is normally to build a PC that's as close as possible to actual Intel Mac hardware—most crucially, the CPU, GPU, and chipset. OpenCore's job is to bridge whatever gap is left between your PC and real Mac hardware so that macOS boots and works properly. It adds support for reading and booting macOS filesystems, loads kernel extensions to support additional hardware, tells macOS how to handle your system's audio outputs and USB ports, and spoofs hardware to take advantage of macOS's built-in support (if, for example, your PC has a GPU that is similar to but not quite identical to a GPU included in a real Intel Mac).

As OpenCore has developed and matured, it has gotten better at bridging larger and larger gaps between PC hardware and "real" Macs. It can get old versions of macOS like Tiger (10.4) and Snow Leopard (10.6) up and running on old hardware, and it can even be used to run newer macOS versions on real Macs that Apple has dropped from the official support list. It can even run macOS on AMD processors, albeit with some caveats for software that relies on Intel-specific functionality. The still-active Hackintosh Reddit community is full of people running macOS on all kinds of different hardware.

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Apple may be done with Intel Macs, but Hackintoshes can still use the newest CPUs

OpenCore project continues bridging the gaps between PCs and real Intel Macs.

Hackintoshes are PCs that run macOS, which means you can do whatever you want with the design.

Enlarge / Hackintoshes are PCs that run macOS, which means you can do whatever you want with the design. (credit: Dan Counsell)

Apple hasn't stopped selling Intel Macs just yet, but it's safe to say that we'll never see a Mac with one of Intel's 12th-generation Core processors in it. But that minor detail isn't stopping the Hackintosh community from supporting new Intel and AMD processors and platforms. The developers behind OpenCore, the most powerful and actively maintained bootloader for loading macOS on standard PC hardware, improved its Alder Lake support in this month's release, version 0.7.7. In a blog post over the weekend, the developers also detailed their efforts to update OpenCore and its associated software to work with Intel's Z690 chipset.

The key to building a functional Hackintosh is normally to build a PC that's as close as possible to actual Intel Mac hardware—most crucially, the CPU, GPU, and chipset. OpenCore's job is to bridge whatever gap is left between your PC and real Mac hardware so that macOS boots and works properly. It adds support for reading and booting macOS filesystems, loads kernel extensions to support additional hardware, tells macOS how to handle your system's audio outputs and USB ports, and spoofs hardware to take advantage of macOS's built-in support (if, for example, your PC has a GPU that is similar to but not quite identical to a GPU included in a real Intel Mac).

As OpenCore has developed and matured, it has gotten better at bridging larger and larger gaps between PC hardware and "real" Macs. It can get old versions of macOS like Tiger (10.4) and Snow Leopard (10.6) up and running on old hardware, and it can even be used to run newer macOS versions on real Macs that Apple has dropped from the official support list. It can even run macOS on AMD processors, albeit with some caveats for software that relies on Intel-specific functionality. The still-active Hackintosh Reddit community is full of people running macOS on all kinds of different hardware.

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Google hired union-busting consultants to convince employees “unions suck”

NLRB judge orders Google to shed light on its secret anti-union project.

A Google employee holds a sign during a walkout to protest how the tech giant handled sexual misconduct at Jackson Square Park in New York on Thursday, Nov. 1, 2018.

Enlarge / A Google employee holds a sign during a walkout to protest how the tech giant handled sexual misconduct at Jackson Square Park in New York on Thursday, Nov. 1, 2018. (credit: Peter Foley/Bloomberg)

For years, Google has attempted to kill employee-led unionization efforts under an initiative codenamed “Project Vivian.” In the words of one senior manager, Project Vivian existed “to engage employees more positively and convince them that unions suck.”

Project Vivian appears to be Google’s response to a surge in worker activism that began in 2018, when thousands of employees walked out in protest of the company’s response to sexual harassment complaints. Months later, employees began pushing for improved working conditions for Google contractors and an end to contracts with US government agencies involved in deportations and family separations. Two employees who helped organize the 2018 walkout later left the company, saying they were facing retaliation.

Ultimately, five employees were fired, and two were disciplined. They filed a complaint with the National Labor Relations Board alleging that Google interfered with their law-protected rights to organize at the workplace. The NLRB agreed and filed a complaint against Google in December 2020. Google refused to settle, and the matter went to the NLRB’s administrative court.

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Did a large impact remix the Moon’s interior?

New model suggests a big impact roiled the Moon’s interior, altered its volcanism.

Image of a red and green sphere with a large blue oval in the center.

Enlarge / The blue area is the basin formed by the largest impact on the Moon. Additional craters have formed by subsequent impacts. (credit: NASA/GSFC/University of Arizona)

As the Moon coalesced from the debris of an impact early in the Solar System's history, the steady stream of orbital impacts is thought to have formed a magma ocean, leaving the body liquid. That should have allowed its components to mix evenly, creating a roughly uniform body. But with the onset of space exploration, we were finally able to get our first good look at the far side of the Moon.

It turned out to look quite different from the side we were familiar with, with very little in the way of the dark regions, called mare, that dominate the side facing Earth. These differences are also reflected in the chemical composition of the rocks on the different sides. If the whole Moon was once a well-mixed blob of magma, how did it end up with such a major difference between two of its faces? A new study links this difference to the Moon's largest impact crater.

A big crash

The South Pole-Aitken Basin is one of the largest impact craters in the Solar System, but again, we didn't realize it was there until after we put a craft in orbit around the Moon. All we can see from Earth are some of the ridges that are part of the outer crater wall. Most of the 2,500 kilometers of the crater itself extend into the far side of the Moon.

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Svalbard Undersea Cable System: Wichtiges arktisches Seekabel teilweise ausgefallen

Ausgerechnet an einem Punkt, wo das Seekabel auf 2.700 Meter steil in die Tiefsee geht, gab es einen Stromausfall. Eines der Twinkabel ist betroffen. (Seekabel, Telekommunikation)

Ausgerechnet an einem Punkt, wo das Seekabel auf 2.700 Meter steil in die Tiefsee geht, gab es einen Stromausfall. Eines der Twinkabel ist betroffen. (Seekabel, Telekommunikation)

Lenovo Tab M10 (3rd-gen) will be a budget tablet with an FHD display and unexpected processor

The Lenovo Tab M10 is a budget Android tablet with a 10.1 inch display. The 2nd-gen model currently sells for $150 and up and features an HD display and a MediaTek Helio P22T processor. But it looks like Lenovo may have a 3rd-gen model on the way which will bring a higher-resolution display and an […]

The post Lenovo Tab M10 (3rd-gen) will be a budget tablet with an FHD display and unexpected processor appeared first on Liliputing.

The Lenovo Tab M10 is a budget Android tablet with a 10.1 inch display. The 2nd-gen model currently sells for $150 and up and features an HD display and a MediaTek Helio P22T processor.

But it looks like Lenovo may have a 3rd-gen model on the way which will bring a higher-resolution display and an unusual processor.

via MySmartPrice

According to MySmartPrice, a page for a Lenovo Tab M10 (3rd-gen) tablet recently showed up at the Google Play Console, which is a resource Android app developers can use to ensure their software is compatible with a wide range of Android phones, tablets, and other devices.

As such, the console provides some key specs about the previously unannounced tablet, including the fact that it will have a 1920 x 1200 pixel display, 4GB of RAM, and a Socionext SC1408J1 processor.

Socionext isn’t exactly a big name in the chip space, but the company makes custom processors for clients, and the name of the SC1408J1 suggests it’s similar to the SC1408H product that Socionet offers for 8K TV devices.

Fortunately we don’t really need to do too much detective work to find specs, as they’re shown in the Google Play Console listing. The chip appears to be a quad-core processor with two ARM Cortex-A72 CPU cores, two Cortex-A53 cores, and ARM Mali-T820 3-core graphics. While that means the new tablet has fewer CPU cores than the 2nd-gen model, two of them are higher-performance CPU cores which could make a difference in performance. The fact that all CPU cores are set to 1.1 GHz seems strange, but it’s probably a good idea to take some of the details shown in the Google Play Console with a grain of salt until Lenovo officially launches the tablet.

For example, the listing says the tablet’s 1920 x 1200 pixel display has 240 pixels per inch, suggesting it has a 9.4 inch display panel. But I suspect the tablet will have a 10.1 inch screen, much like its predecessor.

Based on what we’ve seen so far though, here’s how the Lenovo Tab M10 (3rd-gen) stacks up against the older 2nd-gen model:

Lenovo Tab M10 (3rd-gen) Lenovo Tab M10 (2nd-gen)
Display 1920 x 1200 pixels 10.1 inches
1280 x 800 pixels
CPU Socionext SC1408J1
2 x ARM Cortex-A72 @ 1.1 GHz
2 x ARM Cortex-A53 @ 1.1 GHz
MediaTek Helio P22T
4 x ARM Cortex-A53 @ 2.3 GHz
4 x ARM Cortex-A53 @ 1.8 GHz
CPU ARM Mali-T820 MP3 @ 650 MHz PowerVR GE8320
RAM 4GB? 2GB or 4GB
Storage N/A 32GB or 64GB
Cameras N/A 8MP rear (auto-focus)
5MP front (fixed-focus)
Wireless N/A WiFi 5
Bluetooth 5.0
GPS
Ports N/A USB-C
3.5mm audio
2-point pogo pins
Other N/A Dual Speakers tune by Dolby Atmos
Face unlock
OS Android 11 Android 10

While I wasn’t able to find the Lenovo Tab M10 (3rd-gen) page in the Google Play Console, I did find a mention of the “lenovo tb328fu” model number elsewhere in Google’s Android developer documentation.

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You can no longer call an Uber with your Apple Watch

Uber is still available on the smartwatch, but you can’t do anything with it.

Apple Watch Series 7.

Enlarge / Apple Watch Series 7. (credit: Apple)

Uber has gone the way of Lyft, canceling support for its app on Apple Watches. As spotted by MacRumors Monday, the Uber Apple Watch app is still available but won't let you hail a ride if installed.

We checked on an Apple Watch Series 7 and got a message reading, "Please switch to the Uber mobile app. We no longer support the Apple Watch app. Sorry for the inconvenience," followed by a crying-face emoji.

Like Uber's app for iPhones and iPads, the Apple Watch app let you call a ride from your device, but some features, like Uber Pool, fare splitting, and the ability to contact your driver or share your estimated time of arrival with contacts, were disabled.

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Overwatch-themed Lego set on pause amid Activision abuse allegations

Toymaker is “reviewing” its wider partnership with the Overwatch publisher.

This Lego set will no longer be launching on Feb. 1 as originally planned.

Enlarge / This Lego set will no longer be launching on Feb. 1 as originally planned. (credit: Jay's Brick Blog)

The Lego Group has decided not to release a new Overwatch 2-themed Lego set as planned on February 1, halting the product at least temporarily as the company reviews its wider relationship with the embattled game publisher.

In a statement reported by fan sites like BrickSet and TheBrickFan, Lego Group says that it is "currently reviewing our partnership with Activision Blizzard, given concerns about the progress being made to address continuing allegations regarding workplace culture, especially the treatment of female colleagues and creating a diverse and inclusive environment." As that review continues, the company says it will "pause" the planned release of set 76980, themed after the Overwatch 2 Titan, which was first leaked last month. It's currently unclear how long that "pause" will last or if the set will see an eventual release given Lego's internal partnership review.

The partnership between Overwatch and Lego dates back to 2018 and encompasses nearly a dozen building sets and kits themed after characters and scenes from the game. Activision Blizzard separately signed a deal with Hasbro in 2018 for exclusive rights to license Overwatch toys, among many other branded licensing deals for the popular game.

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