November 2021 – Page 82 – news.buyenne.com

Corona-Lage in Österreich nach Schönwetterpolitik außer Kontrolle

Zögerlichkeit, Regierungszwist und der Zwang, Partikularinteressen zu bedienen, haben die Zahl der Neuinfektionen bedrohlich ansteigen lassen. Jetzt droht ein neuer Lockdown

Open-sourcing of protein-structure software is already paying off

The big trade-off is between computational intensity and the size of the complex.

Image of different categories of protein complexes.

It is now relatively trivial to determine the order of amino acids in a protein. Figuring out how that order translates to a complicated three-dimensional structure that performs a specific function, however, is extremely challenging. But after decades of slow progress, Google's DeepMind AI group announced that it has made tremendous strides toward solving the problem. In July, the system, called AlphaFold, was made open source. At the same time, a group of academic researchers released its own protein-folding software, called RoseTTAFold, built in part using ideas derived from DeepMind's work.

How effective are these tools? Even if they aren't as good as some of the statistics suggested, it's clear they're far better than anything we've ever had. So how will scientists use them?

This week, a large research collaboration set the software loose on a related problem: how these individual three-dimensional structures come together to form the large, multi-protein complexes that perform some of the most important functions in biology.

Read 19 remaining paragraphs | Comments

Kindesmissbrauch: EU-Innenminister unterstützen Pläne für Chatkontrolle

Die EU-Mitgliedstaaten wünschen sich von Kommunikationsdiensten und Providern die “proaktive” Erkennung und Meldung von Kindesmissbrauch. (Ende-zu-Ende-Verschlüsselung, Google)

Die EU-Mitgliedstaaten wünschen sich von Kommunikationsdiensten und Providern die "proaktive" Erkennung und Meldung von Kindesmissbrauch. (Ende-zu-Ende-Verschlüsselung, Google)

ISP Verizon Fails to Lift MangaDex Blockade, Manga Site Codes Own Solution

In the summer subscribers to ISP Verizon found they were being prevented from accessing giant manga scanlation site MangaDex. The US ISP hasn’t provided any reason for taking this action so in response, MangaDex has been working on a solution. Over the past few months, the team has developed a workaround and while it may not last forever, the site is accessible to all once again.

From: TF, for the latest news on copyright battles, piracy and more.

It is extremely common for internet service providers to prevent their customers from accessing pirate sites. Often they are required to do so by after being ordered by a court but in the United States this is almost unknown.

That’s why in the summer it was a surprise to see reports flooding in from Verizon customers alleging they could no longer access a number of pirate sites including MangaDex, NYAA and Kemono.party.

These sites have a few things in common. They all operate in the manga niche, they all have issues with copyright holders, and they all use (or have used) DDoS-Guard, a Russian CDN provider that’s considered a safe haven for pirate sites.

That raised the question of whether the nature of the sites themselves was behind Verizon’s decision to block (or more accurately, null-route), or whether the use of DDoS-Guard was the key factor.

Verizon Fails to Unblock MangaDex

With Verizon failing to fix or even acknowledge the issues, subscribers of the ISP have not been able to access MangaDex by ordinary means. VPNs still worked, of course, but as the image of MangaDex’s network map shows, when Verizon interferes with user connections to DDoS-Guard (the straight line pointing down from ‘Users’), none of the infrastructure behind it can be accessed.

Of course, MangaDex could’ve told Verizon subscribers to use a VPN or even cast them aside completely. However, that clearly isn’t the platform’s style. Finding some way to bypass Verizon’s blocking appears to have become a challenge so, over the past several months, the team has been working on it.

MangaDex Nullifies Verizon’s Null-Route

In a recent announcement, MangaDex revealed that its team has been successful. How they achieved this is being kept a secret for now but the site confirms that its solution works and they received zero help from Verizon.

“To eliminate some misinformation we’ve seen circulate, we would very much like to not thank [Verizon] as they didn’t lift the ban on their end to this day. However, we are really glad to have found a workaround and happy to welcome their users back on the platform,” the team writes.

While this will be a cause for celebration for some Verizon users, MangaDex says that it doesn’t know if the fix will be a permanent one. The best solution, then, would be to switch to an ISP that doesn’t quietly block sites and then offer no explanation.

“We also must mention that there is absolutely no guarantee that our current workaround will last forever, so you might want to consider switching to an ISP that doesn’t censor your internet access at some point. That means pretty much any other one in the world,” the team concludes.

The above image is courtesy of MangaDex which recently published an intriguing overview of its operations

From: TF, for the latest news on copyright battles, piracy and more.

Chipkrise: Teslas wegen Teilemangel ohne USB-Anschlüsse ausgeliefert

Frischgebackene Tesla-Besitzer sind ratlos: Zahlreiche Tesla Model 3 und Model Y sind mit fehlenden USB-Anschlüssen ausgeliefert worden. (Tesla, Technologie)

Olaf Scholz, der BDI und die "letzte Generation"

Ein Gespräch, dass es ohne Hungerstreik nicht gegeben hätte – und warum klar war, dass der SPD-Politiker und die Aktiven der Klimabewegung aneinander vorbeireden würden

Doom’s creator goes after “Doomscroll”

Metal guitarist thinks Doomscroll is a great name for a band. Id Software disagrees.

Dustin Mitchell was scanning the local news one day when inspiration struck in an unlikely article. The report was on a woman who, in a fit of QAnon mania, had destroyed a display of face masks at a Scottsdale, Arizona, Target store. The woman later explained what brought her to that point: “All I did was doomscroll,” she said, referring to her voracious consumption of disastrous news on social media. Something in Mitchell clicked.

“That’s a killer name for a band,” thought Mitchell, a metal guitarist in Dallas, Texas. “I got to do that.”

Read 12 remaining paragraphs | Comments