December 2020 – Page 96 – news.buyenne.com

Malware: BND sucht skrupellose Anfänger zum Trojanerbau

Die Schlapphüte suchen Cyber-Programmierer ohne Gewissen und bieten dafür Peanuts. Das stärkt das Vertrauen in die Unfähigkeit der Behörde. Ein IMHO von Sebastian Grüner (IMHO, Onlinedurchsuchung)

Temperatur-Rekord: November war so warm wie nie

Die Erde nähert sich rasch der 1,5-Grad-Grenze, die eigentlich nicht überschritten werden sollte

Neue Post & DHL App: Briefe mit App und Kugelschreiber frankieren

Endlich eine kluge Lösung für das leidige Briefmarkenproblem, das die Deutsche Post selbst mitverschuldet hat. Von Achim Sawall (Post, Paypal)

A promising start to new human gene-editing trials

Treatments involve adding a new gene, or using CRISPR to edit one.

Image of a patient in bed being attended by three doctors.

Gene therapy has had a long and sometimes difficult history. Plenty of human genetic disorders can be traced to problems with a single gene, and that makes them a tempting target for correction. But someone died in a very early gene-therapy trial, which set the entire field back considerably. And, despite a far more cautious approach, the risks are still considerable, as two deaths during a trial occurred just this year.

But for researchers in the field, and those suffering from genetic diseases, this week provides some hope that the field's long-delayed promise might eventually be met. At a virtual scientific conference, a group presented the results of a large safety trial that saw 50 of 52 patients able to discontinue treatments for hemophilia. And a separate paper describes the use of CRISPR gene-editing and a blood stem cell transplant to successfully treat patients with sickle cell anemia or a related disorder.

Restoring clotting

The hemophilia trial was typical of most early efforts at gene therapy. In this case, the disease is caused by a defect in a single gene, so providing cells with a new copy will correct the problem. And, since the protein that's encoded by that gene circulates in the blood, you don't have to target a small and potentially difficult-to-access population of cells in order to correct things—targeting a new copy of the gene to any cells that can export proteins to the bloodstream will work.

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Intel: Autonomes Programm findet Fehler in Code

Mit Controlflag stellt Intel ein automatisiertes Tool für das Debugging von Quellcode vor. (Intel, Softwareentwicklung)

High-end SATA SSD shootout: Samsung 860 Pro vs. Kingston DC500M

Kingston’s DC500M is a lesser-known drive but a great value for business.

Computer components sit on a woodgrain desk.

Today, we're going to put to good use some of what we covered last year in our Storage Fundamentals series—specifically, we'll use fio to test two competing high-end SATA SSDs.

Each disk has its high points and its low points, and we'll cover both in detail as well as giving you some handy charts to compare the two directly.

Samsung 860 Pro 1TB

The Samsung 860 Pro is a well-respected prosumer drive, tending to lead charts in both performance and endurance. (credit: Samsung)

Samsung's 860 Pro is a staple of the prosumer industry. The 860 Pro marries raw, screaming performance to solid firmware and high write endurance, while remaining accessible for consumers and small businesses. I've personally deployed hundreds of the 840 Pro, 850 Pro, and 860 Pro series of drives to good effect and with no complaints—which is more than I can say for quite a few of Samsung's competitors.

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