At this point, alarmist headlines about the end of the antibiotic era may seem a lot like those car alarms that periodically go off on your street: distracting, annoying, and probably nothing worth panicking over. After all, despite years of distressing headlines, drug-resistant superbugs have yet to rain down upon the public, striking the otherwise healthy with deadly, incurable infections.
Yet, the unfortunate reality is that the longstanding challenge of drug resistance is cause for concern and action. Bacteria have been developing resistance to powerful antibiotics ever since the drugs were first introduced in the 1930s. In some cases, bacteria developed widespread resistance in years and sometimes months after a new drug came out. And bacteria are building up ever more extensive immunity thanks to current practices of overusing and misusing the drugs—antibiotics given thoughtlessly for mild illnesses, or used to treat viral infections (which antibiotics don’t fight), or poured into the feed of healthy livestock. Coupled with the sluggish development of new drugs in the past few decades, the public health problem has reached a crisis level.
Right now, drug resistant infections are mainly a threat to those that are already sick and/or in medical facilities. But, if we continue down this path, mundane infections in the otherwise healthy could someday morph into life-threatening ordeals, and simple medical procedures and surgeries may be skipped to avoid risk of infection.