Functional skin—complete with hair and oil glands—grown in lab

Mouse studies pave the way for implantable skin grafts to treat burns and skin diseases.

Transplantation of the bioengineered, 3D tissue using mouse iPS cells labeled with GFP. (credit: Takashi Tsuji, RIKEN)

For the first time, researchers have coaxed a primordial ball of cells into a multi-layered, transplantable patch of skin, sporting hair follicles and functioning glands.

The mouse-based study, published in Science Advances, brings scientists closer to pulling off the feat in humans, which would provide synthetic skin grafts that could treat burn victims and patients with various skin diseases. “We are coming ever closer to the dream of being able to recreate actual organs in the lab for transplantation and also believe that tissue grown through this method could be used as an alternative to animal testing of chemicals,” lead researcher Takashi Tsuji, of the RIKEN Center for Developmental Biology in Japan, said in a statement.

Researchers have been getting better and better and recreating tissues in lab—but for skin, they had gotten stuck at making simplified versions. Fully functioning skin includes three layers: the epidermis, an outermost protective layer that is mostly waterproof; the elastic dermis layer that gives skin flexibility as well as housing oil and sweat glands, hair follicles, nerve endings, and blood vessels; and the subcutaneous fatty layer that provides padding and insulation.

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WiFi: Brocade kauft Ruckus Wireless für 1,2 Milliarden US-Dollar

Brocade übernimmt den führenden Hersteller von WiFi-Ausstattung Ruckus Wireless. Der Hersteller von professionellen Hotspots baut seine Geräte für Indoor und Outdoor. (WLAN, PC-Hardware)

Brocade übernimmt den führenden Hersteller von WiFi-Ausstattung Ruckus Wireless. Der Hersteller von professionellen Hotspots baut seine Geräte für Indoor und Outdoor. (WLAN, PC-Hardware)

Hot lithium-air battery preserves its electrodes

Heat and salt slows oxidation, leaves electrodes cleaner.

A worker moves crates for batteries on an assembly line at the A123 Systems lithium ion automotive battery manufacturing plant... but maybe someday will move on to lithium-oxygen? (credit: Getty Images)

Battery research is a fraught area to report on. In the lab, researchers manage to show something spectacular, like high current density or excellent recharge characteristics. But the part where the battery catches fire and destroys the lab is left out when the story makes the popular press. I am guilty of this myself, and I'm about to do it again. (Not really.)

Lithium-oxygen batteries are very promising, but most current iterations manage to destroy themselves after a few charge/discharge cycles. A recent publication in the Journal of the American Chemical Society shows some progress in overcoming the problems associated with lithium-oxygen batteries.

Why lithium-oxygen?

We all love our lithium ion batteries. Even though they are the best that we have, they still suck pretty hard. To put it in perspective, lithium ion batteries top out at about 200mAh/g, so you need a very heavy battery to get much energy. Lithium-oxygen, on the other hand, promises 1675mAh/g, a very respectable energy density.

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Quadro M5500: Die erste Mobile-Workstation-GPU für Virtual Reality

Nvidias neue Workstation-Grafikeinheit Quadro M5500 entspricht der Geforce GTX 980 für Notebooks und ist damit flott genug für Head-mounted Displays wie das Oculus Rift oder HTCs Vive. (Grafikhardware, Nvidia)

Nvidias neue Workstation-Grafikeinheit Quadro M5500 entspricht der Geforce GTX 980 für Notebooks und ist damit flott genug für Head-mounted Displays wie das Oculus Rift oder HTCs Vive. (Grafikhardware, Nvidia)

FCC’s “nutrition labels” for broadband show speed, caps, and hidden fees

New labels will help ISPs comply with net neutrality transparency rules.

The Federal Communications Commission today unveiled new broadband labels modeled after the nutrition labels commonly seen on food products. Home Internet service providers and mobile carriers are being urged to use the labels to give consumers details such as prices (including hidden fees tacked onto the base price), data caps, overage charges, speed, latency, packet loss, and so on.

ISPs aren't required to use these labels. But they are required to make more specific disclosures as part of transparency requirements in the FCC's net neutrality order, which reclassified Internet providers as common carriers under Title II of the Communications Act. The FCC recommends that ISPs use these labels to comply with the disclosure rules and says use of the labels will act as a "safe harbor" for demonstrating compliance. However, ISPs can come up with their own format if they still make all the required disclosures in "an accurate, understandable, and easy-to-find manner," the FCC said today.

The labels were approved unanimously by the FCC's Consumer Advisory Committee, a group with both consumer advocates and industry representatives. ISPs on the committee include CenturyLink, Verizon, and T-Mobile USA. The National Cable & Telecommunications Association, the primary lobby group for the cable industry, is also on the committee.

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Top Silk Road 2.0 admin “DoctorClu” pleads guilty, could face 8 years in prison

Brian Farell told feds: “You’re not going to find much of a bigger fish than me.”

(credit: Judit Klein)

Last week, a federal judge in Washington formally accepted the guilty plea of Brian Farrell, the 28-year-old who had been accused in 2015 of being the right-hand man to the head of Silk Road 2.0, the copycat website inspired by the infamous Tor-enabled drug website.

In a 2015 press release, the Department of Justice said that SR2 had generated approximately $8 million per month since it began in November 2013.

Farrell pleaded guilty in March 2016 to one count of distribution of heroin, cocaine, and methamphetamine last month, which carries a minimum sentence of five years in prison. He will also be required to forfeit items that were seized at his arrest in Bellevue, Washington, which included $3,900 in silver bullion bars, $35,000 in cash, and "various computer media." Both Farrell’s lawyers and prosecutors have agreed to a sentence of eight years, but the judge is allowed to impose a harsher sentence if he chooses. (By comparison, Ross Ulbricht, who was convicted of running the original Silk Road, was sentenced in 2015 to a dual life sentence.)

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The modular Nex Band makes smart alerts more customizable than ever

It does a little bit of everything, but is a world of possibilities too much to handle?

(credit: Valentina Palladino)

We're still trying to figure out what we want our wearables, particularly wristbands, to do for us. There are a number of devices including some smartwatches and fitness trackers that are truly multipurpose, but we have yet to see what features will stick in the long run. Now, a company called Mighty Cast is taking a slightly different approach to smart wristbands with its Nex Band—it's made to do pretty much anything that an existing fitness tracker or smartwatch can already do. It monitors activity and receives smartphone alerts, but you can personalize notifications and actions as much as you want by "hacking" its small, removable modules, creating numerous possibilities for new features.

The Nex Band has been floating around for the past couple years, but it has the chance to entice the most enterprising wearable users by giving them more personalization options than any other wristband. Mighty Cast bills it as a hackable smart band because you can assign functions to each of its five "mods" that are all independent from each other and can relate to different things. You might tap on of your mods to turn on your living room lights, while the mod next to it flashes when you receive an e-mail from your boss. A nearly infinite number of functions can be customized from within the Nex Band's companion app, and it's also compatible with all of IFTTT's control combinations.

When I sat down with Mighty Cast's CEO Adam Adelman to learn more about the Nex Band, I was initially confused as to how it worked. However, you don't need to be a developer or have special tech skills to "hack" the band—it's all done from the companion app. Once you choose which mod you want to customize, a basic hack has a two-step "when X happens, do Y" formula. It's really similar to how IFTTT sets up its automated actions by integrating social media, smartphone alerts, IoT products, and other devices to work more for you. For example, you could program a hack that say "when I double-tap, play My Workout Playlist." Then when you completed that action on that mod, your smartphone will start to play that particular playlist.

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To dodge crypto, undercover UK cops simply asked to see terror convict’s iPhone

No need for backdoors or weakened encryption when clever policing does the job.

(credit: CNN)

Key evidence that helped convict two British men last week for terrorist offences was reportedly obtained from a locked phone using a simple but highly effective ruse.

According to CNN, which cited a source close to the investigation, undercover police officers visited Junead Khan, 25, of Luton posing as company managers and asked to check his driver and work records.

"When they disputed where he was on a particular day, he got out his iPhone and showed them the record of his work. The undercover officers asked to see his iPhone and Khan handed it over," CNN reported. At that point they apparently arrested Khan and changed the password settings on the iPhone to prevent it from becoming locked.

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$85 million patent verdict, largest ever against Google, wiped out on appeal

Patent describes a failed company’s 1996 desktop notification system.

Google nearly had to pay $85 million over a 1996 patent said to cover Android's push notifications. (credit: Johan Larsson)

In 2014, an East Texas jury ordered Google to pay $85 million to SimpleAir, a "patent troll" company with no business beyond enforcing its patents. It was a massive victory for the company's broad claim—that Google's use of push notifications in Android phones infringed its US Patent No. 7,035,914.

SimpleAir's victory, the largest patent verdict ever won against Google, has since fallen apart. Google appealed the ruling, and on Friday a three-judge panel at the US Court of Appeals for the Federal Circuit held (PDF) that the lower court judge didn't interpret the patent claims correctly and that Google does not infringe.

The ruling is another signpost that while low-level patent trolling is thriving, the era of large patent troll victories may be waning. The chances of well-resourced tech companies like Google, if they're willing to fight through an appeal, appear better than ever.

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Japanese X-ray observatory seen spinning out of control

Much anticipated X-ray observatory a big loss to scientific community.

Pieces of Japan's Hitomi satellite are seen tumbling through the Orion constellation Sunday night. (credit: William Keel)

The prognosis wasn't good last week when the Japanese Space Agency, JAXA, lost communication with its new Hitomi X-ray astronomy satellite. However, there was some hope a few days later when the space agency reestablished intermittent contact with the spacecraft orbiting some 580km above the Earth.

Astronomers have since been observing the satellite, originally known as Astro-H, as it has orbited around the Earth. The photos with this story, captured by University of Alabama astronomer William Keel on Sunday evening, appear to show different pieces of the spacecraft catching the Sun as they slowly rotate. The brightest moments are probably caused by solar panels spinning into view. The pattern of brighter and then fainter light suggests at least two large pieces, with different periods, are tumbling out of control.

One astronomer who has been tracking Hitomi closely, Jonathan McDowell at the Harvard-Smithsonian Center for Astrophysics, tweeted on Sunday evening, "Sadly, I now believe that the radio signals were the dying sighs of a fatally wounded Astro-H."

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