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Earlier this month, the Trump administration made nine elite universities an offer they couldn’t refuse: bring in more conservatives while shutting down “institutional units that purposefully punish, belittle, and even spark violence against conservative ideas,” give up control of admissions and hiring decisions, agree to “biological” definitions of sex and gender, don’t raise tuition for five years, clamp down on student protests, and stay institutionally “neutral” on current events. Do this and you won’t be cut off from “federal benefits,” which could include research funding, student loans, federal contracts, and even student and faculty immigration visas. Instead, you may gain “substantial and meaningful federal grants.”

But the universities are refusing. With the initial deadline of October 20 approaching, four of the nine universities—the University of Pennsylvania, Brown, University of Southern California, and MIT—that received the federal “compact” have announced that they will not sign it. [Update: A fifth school, the University of Virginia, has now declined the deal.]

In addition, the American Council on Education, which represents more than 1,600 colleges and universities, today issued a statement calling for the compact to be completely withdrawn.

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For some cases of bacterial vaginosis, treatment should include a package deal, doctors now say.

The American College of Obstetricians & Gynecologists (ACOG) updated its clinical guidance Friday to fit with recent data indicating that treatment for recurring bacterial vaginosis (BV) in women is significantly more effective if their male partners are also treated at the same time—with both an oral antibiotic and an antibiotic cream directly onto the potentially offending member.

“Partner therapy offers us another avenue for hopefully preventing recurrence and helping people feel better faster,” Christopher Zahn, chief of clinical practice and health equity and quality at ACOG, said in a statement.

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Law enforcement agencies will soon have easier access to footage captured by Amazon’s Ring smart cameras. In a partnership announced this week, Amazon will allow approximately 5,000 local law enforcement agencies to request access to Ring camera footage via surveillance platforms from Flock Safety. Ring’s cooperation with law enforcement and the reported use of Flock technologies by federal agencies, including US Immigration and Customs Enforcement (ICE), has resurfaced privacy concerns that have followed the devices for years.

According to Flock’s announcement, its Ring partnership allows local law enforcement members to use Flock software “to send a direct post in the Ring Neighbors app with details about the investigation and request voluntary assistance.” Requests must include “specific location and timeframe of the incident, a unique investigation code, and details about what is being investigated,” and users can look at the requests anonymously, Flock said.

“Any footage a Ring customer chooses to submit will be securely packaged by Flock and shared directly with the requesting local public safety agency through the FlockOS or Flock Nova platform,” the announcement reads.

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In 1890, a German scientist named Robert Koch thought he’d invented a cure for tuberculosis, a substance derived from the infecting bacterium itself that he dubbed Tuberculin. His substance didn’t actually cure anyone, but it was eventually widely used as a diagnostic skin test. Koch’s successful failure is just one of the many colorful cases featured in Dead Ends! Flukes, Flops, and Failures that Sparked Medical Marvels, a new nonfiction illustrated children’s book by science historian Lindsey Fitzharris and her husband, cartoonist Adrian Teal.

A noted science communicator with a fondness for the medically macabre, Fitzharris published a biography of surgical pioneer Joseph Lister, The Butchering Art, in 2017—a great, if occasionally grisly, read. She followed up with 2022’s  The Facemaker: A Visionary Surgeon’s Battle to Mend the Disfigured Soldiers of World War I, about a WWI surgeon named Harold Gillies who rebuilt the faces of injured soldiers.

And in 2020, she hosted a documentary for the Smithsonian Channel, The Curious Life and Death Of…, exploring famous deaths, ranging from drug lord Pablo Escobar to magician Harry Houdini. Fitzharris performed virtual autopsies, experimented with blood samples, interviewed witnesses, and conducted real-time demonstrations in hopes of gleaning fresh insights. For his part, Teal is a well-known caricaturist and illustrator, best known for his work on the British TV series Spitting Image. His work has also appeared in The Guardian and the Sunday Telegraph, among other outlets.

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Texas is being sued by a Big Tech lobby group over the state’s new law that will require app stores to verify users’ ages and impose restrictions on users under 18.

“The Texas App Store Accountability Act imposes a broad censorship regime on the entire universe of mobile apps,” the Computer & Communications Industry Association (CCIA) said yesterday in a lawsuit. “In a misguided attempt to protect minors, Texas has decided to require proof of age before anyone with a smartphone or tablet can download an app. Anyone under 18 must obtain parental consent for every app and in-app purchase they try to download—from ebooks to email to entertainment.”

The CCIA said in a press release that the law violates the First Amendment by imposing “a sweeping age-verification, parental consent, and compelled speech regime on both app stores and app developers.” When app stores determine that a user is under 18, “the law prohibits them from downloading virtually all apps and software programs and from making any in-app purchases unless their parent consents and is given control over the minor’s account,” the CCIA said. “Minors who are unable to link their accounts with a parent’s or guardian’s, or who do not receive permission, would be prohibited from accessing app store content.”

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The Orion spacecraft, which will fly four people around the Moon, arrived inside the cavernous Vehicle Assembly Building at NASA’s Kennedy Space Center in Florida late Thursday night, ready to be stacked on top of its rocket for launch early next year.

The late-night transfer covered about 6 miles (10 kilometers) from one facility to another at the Florida spaceport. NASA and its contractors are continuing preparations for the Artemis II mission after the White House approved the program as an exception to work through the ongoing government shutdown, which began on October 1.

The sustained work could set up Artemis II for a launch opportunity as soon as February 5 of next year. Astronauts Reid Wiseman, Victor Glover, Christina Koch, and Jeremy Hansen will be the first humans to fly on the Orion spacecraft, a vehicle that has been in development for nearly two decades. The Artemis II crew will make history on their 10-day flight by becoming the first people to travel to the vicinity of the Moon since 1972.

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Backblaze is a backup and cloud storage company that has been tracking the annualized failure rates (AFRs) of the hard drives in its datacenter since 2013. As you can imagine, that’s netted the firm a lot of data. And that data has led the company to conclude that HDDs “are lasting longer” and showing fewer errors.

That conclusion came from a blog post this week by Stephanie Doyle, Backblaze’s writer and blog operations specialist, and Pat Patterson, Backblaze’s chief technical evangelist. The authors compared the AFRs for the approximately 317,230 drives in Backblaze’s datacenter to the AFRs the company recorded when examining the 21,195 drives it had in 2013 and 206,928 drives in 2021. Doyle and Patterson said they identified “a pretty solid deviation in both age of drive failure and the high point of AFR from the last two times we’ve run the analyses.”

Credit: Backblaze

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Our hominid ancestors faced a Pleistocene world full of dangers—and apparently one of those dangers was lead poisoning.

Lead exposure sounds like a modern problem, at least if you define “modern” the way a paleoanthropologist might: a time that started a few thousand years ago with ancient Roman silver smelting and lead pipes. According to a recent study, however, lead is a much more ancient nemesis, one that predates not just the Romans but the existence of our genus Homo. Paleoanthropologist Renaud Joannes-Boyau of Australia’s Southern Cross University and his colleagues found evidence of exposure to dangerous amounts of lead in the teeth of fossil apes and hominins dating back almost 2 million years. And somewhat controversially, they suggest that the toxic element’s pervasiveness may have helped shape our evolutionary history.

The skull of an early hominid. Credit: Einsamer Schütze / Wikimedia

The Romans didn’t invent lead poisoning

Joannes-Boyau and his colleagues took tiny samples of preserved enamel and dentin from the teeth of 51 fossils. In most of those teeth, the paleoanthropologists found evidence that these apes and hominins had been exposed to lead—sometimes in dangerous quantities—fairly often during their early years.

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